Gallery Structures

Please click on target for specifications

Kinases

ABL1ACK1, ALK, Aurora-AAurora-BBMXB-RafBTK, CDK8/Cyclin C, CHK1c-KitCLK2c-MetCDK2eEF2kinaseEGFREPHA4EPHB4,
ERK-2(MAPK1)ERK-5(MAPK7)FAK1(PTK2)FESFGFR4FLT3GlucokinaseGSK-3ßHPK1IGF1RInsulin ReceptorIRAK-4, IRE1αITK,
JAK1JAK2JAK3JNK1KDR(VEGFR2)LCKLIMK2aMAP3K12, MAP4K3 (GLK)NEW, MAPKAPK2MAPK14(p38a)MEK1(MAP2K1)MEK2, MELKNEW, MNK2MST-1NEK2,
NIKPAK1PAK4PERK1PI3K-αPI3k-γPI3K-δPI4K-ßPIM1PIM2PKA C-αPKB(AKT1)PKC-αPKC-θPKC-ι, PknBNEW, PLK1PLK2PLK4PYK2,
RCKinaseRET, RIPK1NEW, ROCK1ROCK2RONRSK2ROS1Sphingosine_Kinase 1SRCSTK33SYKTAK1(MAP3K7_TAB1)TBK1TIE-2(TEK)TrkA, TYK2, Wee1NEW

Epigenetic Targets

BRD4(Bromo1), Cezanne1DNMT1DNMT3B/3LDOT1L, EHMT2-G9aHDAC4, HDAC2NEW, KDM4A (JMJD2A), KDM4C (JMJD2C)KEAP1,  KDM2ALSD1,
UCHL1USP2USP7USP8USP14   

Apoptosis Regulators

BCL2BCL6BCL-XLMCL1MDM2MDM4    

Others

11-ß-HSD1ACC2(CTD)Aldose reductaseAutotaxin, DNA- Topoisomerase Iß-Catenin, CD73NEW, ClpC1NEW, CyclophilinD(mitoch.)DHODHFAAHFASN,
Ggt (H. pylori)Gyrase A,  Gyrase BHCV NS5A Domain lHCV NS5B PolymeraseHIV1_Reverse_Transcript.HSAHSP 90-αIDO1,
IL-17A, KIF11(KSP/EG5)K-RasLXR-αLXR-ßMTH1NS5 Polymerase(DENV)PARP-1PPAR-γPPAR-δ, PXRNEW, SHP2NEW,TDO DmTGM2TNF-α    

Proteases

ADAMTS5BACE1, BACE2-XaperoneCalpain(μl-ll)Caspase-1Caspase-6Caspase-9Cathepsin BCathepsin DCathepsin H,
Cathepsin KCathepsin L1ChymaseDPP 4DPP 8, DPP 9NEW, Elastase-2Factor VllaFactor IXaFactor XaFactor XlaFAP αHCV_NS3/4A_Protease,
HIV1 Protease, ImmunoproteasomeNEW, MMP-2MMP-9MMP-12MMP-13PCSK9ProteasomeThrombin     

Phosphodiesterases

PDE1BPDE2APDE4APDE4BPDE4D, PDE10A

Biologics